1010Rx

Doxycycline Hyclate — questions and safety.

Back to Doxycycline Hyclate

Common Side Effects:

• Nausea or upset stomach

• Sun sensitivity (photosensitivity)

• Diarrhea

• Mild headache

Less Common:

• Esophageal irritation (take with a full glass of water)

• Yeast infections (oral or genital)

• Allergic reaction (rare)

Precautions:

Not a substitute for HIV PrEP or HPV protection

Avoid prolonged sun exposure while taking

Take with food or water to reduce stomach upset

Do not use during pregnancy

Overuse may contribute to antibiotic resistance—intended for high-risk scenarios, not casual use after every exposure

• Take 1 dose of 200mg doxycycline (usually two 100mg tablets) within 72 hours of condomless sex

• Best used under guidance of a provider familiar with sexual health and STI risk

• Does not protect against viral STIs (e.g., HIV, herpes, HPV)—use in combination with other prevention strategies

• Continue regular STI screening every 3 months

Oral tablets in a bottle

Yes, on every order. A physician licensed in your state reviews your intake before anything is prescribed.

Most treatments ship within 3 days of your clinician's approval. Timing can vary with your provider's review and the pharmacy filling your prescription. Shipping is free and the packaging is plain.

Any time. Dose, form and frequency are all adjustable, and changing costs nothing.

Any time, from your account. No call, no retention offer.

1010Rx, LLC works with a network of licensed dispensing pharmacy partners to fulfill prescriptions written by clinicians on our platform. When a prescription is issued, it is routed to one of these partner pharmacies based on the medication prescribed, the patient’s state of residence, and availability. Each partner pharmacy is independently licensed and responsible for dispensing, labeling, and shipping the medication directly to the patient. Our current pharmacy partners, including the licensed entity name that will appear on your prescription label, may include:

  • DrugStore on East State — The Drugstore at O’Bleness LLC, 934 E State St, Athens, OH 45701 · (740) 566-4690
  • DiRx Health — Direct Pharmacy Source, Inc., 3540 NW 56th St, Ste 204, Fort Lauderdale, FL 33309 · (877) 367-3479
  • Curexa — Curexa Pharmacy, 501 Zion Rd, Ste 13-14, Egg Harbor Township, NJ 08234 · (855) 927-0390
  • Mycelium — Mycelium Pharmacy LLC, 141 E Commercial Blvd, Fort Lauderdale, FL 33334 · (954) 890-1150
  • ChemistryRx — Madame Rx, LLC d/b/a Chemistry Rx, 950 Henderson Blvd, Folcroft, PA 19032 · (855) 790-0100
  • Brooksville Rx — Brooksville Pharmaceuticals, 16140 Flight Path Dr, Brooksville, FL 34604 · (352) 848-3446
  • Epiq Scripts — Epiq Scripts LLC, 465 W President George Bush Hwy, Ste 240, Richardson, TX 75080 · (833) 654-3553
  • Foothills — Foothills Professional Pharmacy Ltd, 2727 W Baseline Rd, Ste 1, Tempe, AZ 85283 · (833) 236-8080
  • Southend — Southend Pharmacy, 4802 N Sam Houston Pkwy W, #100, Houston, TX 77086 · (855) 414-5356
  • Wells — Wells Pharmacy Network, 3420 Fairlane Farms Rd, Wellington, FL 33414 · (800) 622-4510

Certain branded medications are fulfilled through manufacturer self-pay programs rather than our pharmacy network. These include NovoCare Pharmacy (CoAssist Pharmacy, LLC, 2400 Sand Lake Rd, Ste 200B, Orlando, FL 32809 · (833) 949-5527) and LillyDirect (GiftHealth, Inc., 266 N 4th St, Ste 200, Columbus, OH 43215 · (833) 614-4438).

This list may change from time to time.

Full safety information

Common Side Effects:

• Nausea or upset stomach

• Sun sensitivity (photosensitivity)

• Diarrhea

• Mild headache

Less Common:

• Esophageal irritation (take with a full glass of water)

• Yeast infections (oral or genital)

• Allergic reaction (rare)

Precautions:

Not a substitute for HIV PrEP or HPV protection

Avoid prolonged sun exposure while taking

Take with food or water to reduce stomach upset

Do not use during pregnancy

Overuse may contribute to antibiotic resistance—intended for high-risk scenarios, not casual use after every exposure

Prescription items are subject to clinician review before dispensing. After checkout you will complete a medical intake form. A licensed physician reviews it, and if you are approved, your medication ships. Your clinician sets the exact dose during that review.

This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription, and if you are not approved you will not be charged for medication.

Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects and interactions.

Multi-month plans renew automatically at the end of the term until cancelled. Cancel any time before renewal from your account.