Female Hormone Replacement Therapy (HRT) is a physician-guided treatment program designed to help restore hormonal balance during perimenopause and menopause.
Prescription items are subject to clinician review before dispensing. After checkout you will complete a medical intake form. A licensed physician reviews it, and if you are approved, your medication ships. Your clinician sets the exact dose during that review.
This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription, and if you are not approved you will not be charged for medication.
Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects and interactions.
Multi-month plans renew automatically at the end of the term until cancelled. Cancel any time before renewal from your account.
Full safety information
Estradiol is the primary estrogen produced during a woman's reproductive years and plays a critical role in maintaining cardiovascular, bone, brain, skin, and urogenital health.
Replacing estrogen may help reduce hot flashes, night sweats, mood fluctuations, sleep disturbances, vaginal dryness, and cognitive symptoms commonly associated with menopause.
Helps reduce hot flashes and night sweats
Supports healthy sleep and improved mood
Promotes vaginal health and sexual wellness
Helps maintain bone density and muscle mass
Supports cognitive function and mental clarity
Improves skin hydration and elasticity
May enhance libido and quality of life in appropriate candidates
Supports healthy aging and long-term wellness
Personalized physician-guided treatment based on individual needs
• Weeks 1 to 4:
Many women notice early improvements in sleep quality, mood stability, and a reduction in hot flashes or night sweats.
• Weeks 4 to 8:
Energy levels, mental clarity, and overall sense of well-being often continue to improve. Vaginal symptoms may begin to resolve.
• Months 2 to 3:
Many patients experience meaningful improvements in quality of life, sexual wellness, and overall symptom control as hormone levels stabilize.
• Long-term therapy may also support bone health, skin quality, and healthy aging when combined with proper nutrition, exercise, and preventive healthcare.
• Your treatment plan will be individualized and adjusted based on symptoms, laboratory evaluation, and regular physician follow-up.
• Whether you qualify for traditional Hormone Replacement Therapy or a non-hormonal alternative, our goal is the same: helping you regain comfort, confidence, and quality of life through personalized, evidence-based care.
Labs — Dialing in your dose
Estrogen therapy works best when it's measured. Your labs show how your body is responding — and guide every adjustment.
Delivers estradiol through the skin during hormone therapy.
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An estradiol gel to restore estrogen during hormone therapy.
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An estradiol gel to restore estrogen during hormone therapy.
Join the waitlist
An estradiol gel to restore estrogen during hormone therapy.
Join the waitlist