Estriol Vitamin C Hydrolyzed Hyaluronic Acid — questions and safety.

Common (Usually Mild):

• Temporary redness or mild irritation at the application site

• Mild tingling sensation, especially during the first few applications

• Temporary dryness or flaking as the skin adjusts

Less Common / Monitor If Present:

• Allergic reaction to any component of the formulation

• Persistent irritation or rash

• Increased sun sensitivity; daily sunscreen use is recommended

Patients with a history of estrogen-sensitive conditions should discuss appropriate use with their healthcare provider before starting therapy.

• Week 1–2:

Skin feels more hydrated, smoother, and softer with improved moisture retention.

• Week 4–6:

Visible improvements in brightness, texture, and overall skin quality may begin to appear.

• Week 8–12:

Collagen remodeling and enhanced skin elasticity can contribute to a firmer, more youthful appearance with continued use.

• For best results, apply consistently as directed and incorporate daily broad-spectrum sun protection.

• This therapy works well alongside medical-grade skincare regimens and other physician-supervised aesthetic treatments.

• Missed application? Resume your normal schedule at the next application—do not apply extra product to make up for a missed dose.

Topical cream

Yes, on every order. A physician licensed in your state reviews your intake before anything is prescribed.

Most treatments ship within 3 days of your clinician's approval. Timing can vary with your provider's review and the pharmacy filling your prescription. Shipping is free and the packaging is plain.

Any time. Dose, form and frequency are all adjustable, and changing costs nothing.

Any time, from your account. No call, no retention offer.

1010Rx, LLC works with a network of licensed dispensing pharmacy partners to fulfill prescriptions written by clinicians on our platform. When a prescription is issued, it is routed to one of these partner pharmacies based on the medication prescribed, the patient’s state of residence, and availability. Each partner pharmacy is independently licensed and responsible for dispensing, labeling, and shipping the medication directly to the patient. Our current pharmacy partners, including the licensed entity name that will appear on your prescription label, may include:

• DrugStore on East State — The Drugstore at O’Bleness LLC, 934 E State St, Athens, OH 45701 · (740) 566-4690
• DiRx Health — Direct Pharmacy Source, Inc., 3540 NW 56th St, Ste 204, Fort Lauderdale, FL 33309 · (877) 367-3479
• Curexa — Curexa Pharmacy, 501 Zion Rd, Ste 13-14, Egg Harbor Township, NJ 08234 · (855) 927-0390
• Mycelium — Mycelium Pharmacy LLC, 141 E Commercial Blvd, Fort Lauderdale, FL 33334 · (954) 890-1150
• ChemistryRx — Madame Rx, LLC d/b/a Chemistry Rx, 950 Henderson Blvd, Folcroft, PA 19032 · (855) 790-0100
• Brooksville Rx — Brooksville Pharmaceuticals, 16140 Flight Path Dr, Brooksville, FL 34604 · (352) 848-3446
• Epiq Scripts — Epiq Scripts LLC, 465 W President George Bush Hwy, Ste 240, Richardson, TX 75080 · (833) 654-3553
• Foothills — Foothills Professional Pharmacy Ltd, 2727 W Baseline Rd, Ste 1, Tempe, AZ 85283 · (833) 236-8080
• Southend — Southend Pharmacy, 4802 N Sam Houston Pkwy W, #100, Houston, TX 77086 · (855) 414-5356
• Wells — Wells Pharmacy Network, 3420 Fairlane Farms Rd, Wellington, FL 33414 · (800) 622-4510

Certain branded medications are fulfilled through manufacturer self-pay programs rather than our pharmacy network. These include NovoCare Pharmacy (CoAssist Pharmacy, LLC, 2400 Sand Lake Rd, Ste 200B, Orlando, FL 32809 · (833) 949-5527) and LillyDirect (GiftHealth, Inc., 266 N 4th St, Ste 200, Columbus, OH 43215 · (833) 614-4438).

This list may change from time to time.