Hydroquinone 6% / Kojic Acid 6% / Niacinamide 5% Topical is a physician-guided skin brightening and pigmentation correction therapy formulated to improve uneven skin tone and reduce the appearance of stubborn dark spots.
Prescription items are subject to clinician review before dispensing. After checkout you will complete a medical intake form. A licensed physician reviews it, and if you are approved, your medication ships. Your clinician sets the exact dose during that review.
This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription, and if you are not approved you will not be charged for medication.
Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects and interactions.
Multi-month plans renew automatically at the end of the term until cancelled. Cancel any time before renewal from your account.
Full safety information
Hydroquinone is considered the gold standard topical agent for reducing excess pigmentation by inhibiting tyrosinase, the enzyme responsible for melanin production.
Helps gradually fade dark spots and even out skin tone over time.
Kojic Acid is a naturally derived antioxidant that also inhibits tyrosinase activity, complementing the effects of hydroquinone.
Helps improve overall skin radiance while reducing the appearance of discoloration caused by sun exposure and inflammation.
Niacinamide (Vitamin B3) helps reduce the transfer of pigment to skin cells while supporting the skin's natural barrier function.
Calms redness, improves texture, and enhances the overall appearance of the complexion.
Helps reduce melasma and stubborn hyperpigmentation
Fades sun spots, age spots, and post-acne discoloration
Promotes a brighter, more even skin tone
Supports healthier skin barrier function
Reduces redness and improves skin texture
Complements physician-supervised aesthetic treatments
Supports long-term skin rejuvenation protocols
• Week 1–2:
Skin may experience mild dryness or temporary irritation as treatment begins. Consistent use and sun protection are important.
• Week 4–6:
Many patients begin to notice gradual fading of dark spots and a more even complexion.
• Week 8–12:
Continued use may lead to significant improvements in pigmentation, overall brightness, and skin clarity.
*** Discontinue use for 2-3 months after 12 weeks of therapy *** May repeat cycle.
• For best results, apply consistently as directed and use daily broad-spectrum sunscreen.
• This therapy works well alongside physician-guided skincare regimens and aesthetic procedures designed to improve skin tone and texture.
• Missed application? Resume your normal schedule at the next application—do not apply extra product to make up for a missed dose.
Your labs show why — and shape what comes next
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