1010Rx
Hair & Skin

Hydroquinone, Tretinoin, Vitamin C, Niacinamide

Cream
Hydroquinone, Tretinoin, Vitamin C, Niacinamide

This compounded topical therapy combines Hydroquinone, Tretinoin, Niacinamide, and Vitamin C to address unwanted hyperpigmentation and uneven skin tone while supporting skin renewal and tolerability.

Total due now$89
What’s included
  • Clinician consultation
  • Shipping, always free
  • The same price at every dose
  • Message your clinician any time

Prescription items are subject to clinician review before dispensing. After checkout you will complete a medical intake form. A licensed physician reviews it, and if you are approved, your medication ships. Your clinician sets the exact dose during that review.

This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription, and if you are not approved you will not be charged for medication.

Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects and interactions.

Multi-month plans renew automatically at the end of the term until cancelled. Cancel any time before renewal from your account.

Full safety information

What you’re taking

Hydroquinone, Tretinoin, Vitamin C, Niacinamide
01 · Mechanism
Man checking his face in a bathroom mirror

1. Targets Excess Pigment

Hydroquinone inhibits tyrosinase, an enzyme involved in melanin production, helping gradually lighten areas of excess pigmentation.

Woman checking her skin in a hand mirror

2. Promotes Skin Renewal

Tretinoin increases epidermal cell turnover, helping improve skin texture and supporting more even distribution of pigment over time.

Man applying cream to his cheek

3. Supports Tolerability & Skin Barrier

Niacinamide supports barrier function and may help improve the appearance of uneven tone, while Vitamin C helps reduce treatment-related redness and inflammation.

Woman applying cream to her cheek
02 · Benefits

What it’s for

Helps improve the appearance of hyperpigmentation and dark spots

Supports a more even-looking skin tone

Promotes skin-cell turnover and smoother-looking texture

Niacinamide supports the skin barrier

Vitamin C helps reduce redness and irritation

Convenient once-daily topical application

03 · Timeline

What to expect, and when

• Apply a thin layer to the affected areas once a day as directed

• Wash hands before and after application

• Avoid the eyes, lips, corners of the nose, and broken or irritated skin

• Mild dryness, peeling, or irritation may occur when treatment is first started

• Use a gentle cleanser and moisturizer as recommended by your clinician

• Apply broad-spectrum sunscreen every morning because sun exposure can worsen pigmentation and Tretinoin can increase sun sensitivity

• Improvement in discoloration is gradual and consistent use is important

• Contact your clinician for severe irritation, unexpected skin darkening, or other concerning reactions

Hands rubbing in cream
Two laboratory professionals in white coats reviewing results on a tablet beside a microscope

Same dose, different response

Your labs show why — and shape what comes next

Ferritin and ironthe most common reversible cause
Thyroidhair, skin and energy at once
Vitamin Ddeficiency is the default, not the exception
Testosterone and DHTthe hormonal side of the picture
hs-CRPinflammation, quietly
Liver and kidneywhat keeps your dosing safe
See the full panel

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