1010Rx
Hair & Skin

Salicylic Acid / Zinc Oxide / Niacinamide / Urea Cream

Cream
Salicylic Acid / Zinc Oxide / Niacinamide / Urea Cream

Salicylic Acid 2% / Zinc Oxide 5% / Niacinamide 8% / Urea 2% Cream is a physician-guided topical therapy formulated to help manage acne-prone, oily, and irritated skin while supporting the skin's natural barrier.

3 mo · 90 Gram
What’s included
  • Clinician consultation
  • Shipping, always free
  • The same price at every dose
  • Message your clinician any time

Prescription items are subject to clinician review before dispensing. After checkout you will complete a medical intake form. A licensed physician reviews it, and if you are approved, your medication ships. Your clinician sets the exact dose during that review.

This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription, and if you are not approved you will not be charged for medication.

Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects and interactions.

Multi-month plans renew automatically at the end of the term until cancelled. Cancel any time before renewal from your account.

Full safety information

What you’re taking

Salicylic Acid / Zinc Oxide / Niacinamide / Urea Cream
01 · Mechanism
Man checking his face in a bathroom mirror

Salicylic Acid Pore Clarification

Salicylic Acid is a beta-hydroxy acid (BHA) that penetrates into pores to dissolve excess oil and dead skin cells.

Helps reduce blackheads, whiteheads, and acne breakouts while promoting smoother skin texture.

Hands rubbing in cream

Zinc Oxide Skin Soothing

Zinc Oxide provides anti-inflammatory and protective properties that help calm irritated skin.

Supports healing while reducing redness and creating a protective barrier against environmental stressors.

Man applying cream to his cheek

Niacinamide Barrier & Oil Control

Niacinamide (Vitamin B3) helps regulate sebum production and strengthen the skin barrier.

Reduces redness, minimizes the appearance of pores, and promotes a more even complexion.

Smiling woman resting her face in her hands

Urea Gentle Hydration

Urea acts as a natural humectant that attracts moisture while gently softening rough or flaky skin.

Helps offset the drying effects often associated with acne treatments, improving overall skin comfort.

Woman checking her skin in a hand mirror
02 · Benefits

What it’s for

Helps unclog pores and reduce acne breakouts

Controls excess oil production

Calms redness and skin irritation

Improves overall skin texture and smoothness

Supports the skin's natural moisture barrier

Reduces the appearance of enlarged pores

Complements physician-supervised acne and skincare protocols

03 · Timeline

What to expect, and when

• Week 1–2:

Skin may undergo an adjustment period with mild dryness as pores begin to clear and oil production normalizes.

• Week 4–6:

Many patients notice fewer breakouts, smoother skin texture, and a reduction in excess oil and redness.

• Week 8–12:

Continued use may result in clearer, healthier-looking skin with improved tone, balanced hydration, and enhanced skin barrier function.

• For best results, apply consistently as directed and use a gentle cleanser and daily broad-spectrum sunscreen.

• This therapy works well alongside physician-guided acne management and aesthetic skincare programs.

• Missed application? Resume your normal schedule at the next application—do not apply extra product to make up for a missed dose.

Woman applying cream to her cheek
Two laboratory professionals in white coats reviewing results on a tablet beside a microscope

Same dose, different response

Your labs show why — and shape what comes next

Ferritin and ironthe most common reversible cause
Thyroidhair, skin and energy at once
Vitamin Ddeficiency is the default, not the exception
Testosterone and DHTthe hormonal side of the picture
hs-CRPinflammation, quietly
Liver and kidneywhat keeps your dosing safe
See the full panel

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