1010Rx
Hair & Skin

Tretinoin + Niacinamide + HA

Compounded topical
Tretinoin + Niacinamide + HA

Tretinoin / Niacinamide / Hyaluronic Acid is a topical combination designed to support clearer, smoother, and more hydrated-looking skin.

Total due now$89
What’s included
  • Clinician consultation
  • Shipping, always free
  • The same price at every dose
  • Message your clinician any time

Prescription items are subject to clinician review before dispensing. After checkout you will complete a medical intake form. A licensed physician reviews it, and if you are approved, your medication ships. Your clinician sets the exact dose during that review.

This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription, and if you are not approved you will not be charged for medication.

Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects and interactions.

Multi-month plans renew automatically at the end of the term until cancelled. Cancel any time before renewal from your account.

Full safety information

What you’re taking

Tretinoin + Niacinamide + HA
01 · Mechanism
Woman checking her skin in a hand mirror

1. Promotes Skin-Cell Turnover

Tretinoin increases skin-cell turnover, helping prevent buildup of dead skin cells and supporting clearer, smoother-looking skin.

Man checking his face in a bathroom mirror

2. Supports Clearer Pores

Tretinoin can help reduce pore blockage and is commonly used as part of acne treatment.

Woman applying cream to her cheek

3. Supports the Skin Barrier

Niacinamide supports normal skin-barrier function and may help improve the appearance of redness and uneven tone.

Smiling woman resting her face in her hands

4. Provides Hydration

Hyaluronic Acid attracts and retains moisture, helping support skin hydration and a smoother, more supple appearance.

Man applying cream to his cheek
02 · Benefits

What it’s for

Supports clearer-looking skin

Helps improve skin texture

Helps keep pores clear

Supports a more even-looking skin tone

Helps improve the appearance of fine lines and photoaged skin

Supports the skin barrier

Provides added hydration

Convenient once-daily application

03 · Timeline

What to expect, and when

• Apply a thin layer to affected areas once daily as directed.

• Apply to clean, dry skin.

• Dryness, peeling, redness, or mild irritation may occur when treatment is first started.

• Use a gentle moisturizer if recommended by your clinician.

• Use sunscreen and appropriate sun protection during the day.

• Consistent use is important; visible improvement generally occurs gradually rather than immediately.

• Use consistently as directed for best results.

Hands rubbing in cream
Two laboratory professionals in white coats reviewing results on a tablet beside a microscope

Same dose, different response

Your labs show why — and shape what comes next

Ferritin and ironthe most common reversible cause
Thyroidhair, skin and energy at once
Vitamin Ddeficiency is the default, not the exception
Testosterone and DHTthe hormonal side of the picture
hs-CRPinflammation, quietly
Liver and kidneywhat keeps your dosing safe
See the full panel

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