
Viral DNA Inhibition
Valacyclovir stops HSV-1 from replicating by inhibiting the viral DNA polymerase enzyme. This prevents the virus from spreading, helping reduce outbreak severity and duration.

Valacyclovir is an antiviral medication used to treat cold sores (oral herpes), which are caused by the herpes simplex virus type 1 (HSV-1).
Prescription items are subject to clinician review before dispensing. After checkout you will complete a medical intake form. A licensed physician reviews it, and if you are approved, your medication ships. Your clinician sets the exact dose during that review.
This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription, and if you are not approved you will not be charged for medication.
Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects and interactions.
Multi-month plans renew automatically at the end of the term until cancelled. Cancel any time before renewal from your account.
Full safety information
Valacyclovir stops HSV-1 from replicating by inhibiting the viral DNA polymerase enzyme. This prevents the virus from spreading, helping reduce outbreak severity and duration.

By halting viral replication, Valacyclovir speeds up the healing of cold sores and reduces symptoms like pain, burning, and itching.

For patients with frequent recurrences (≥6 per year), daily low-dose Valacyclovir can reduce flare-up frequency, severity, and viral shedding.

Shortens healing time and reduces symptoms
May prevent full development if taken at first sign of outbreak
Reduces frequency and intensity of future outbreaks
Available for both episodic and preventive use
Convenient oral dosing (1–2 doses per day)
Safe for long-term use in most patients
• For episodic use: Take at first sign of outbreak (usually tingling or burning)
• Most patients experience faster healing and reduced symptoms within 2–3 days
• For suppressive use: Daily dosing can reduce outbreak frequency by up to 80%
• Not a cure—virus remains in the body, but outbreaks can be managed effectively
• Missed dose? Take as soon as you remember unless it's almost time for your next dose


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